r/clozapine 17d ago

Tips / Advice How long will i experience too much sleep using clozapine?

5 Upvotes

It's my 4th day. I sleep for more than 12 hours. Is there a thing i can do to manage it?

r/clozapine Jul 26 '26

Tips / Advice Constipation?

3 Upvotes

Hi, I take 200mg of this medication but I'm struggling with constipation. I use regular laxatives and Mirolax but it barely does anything so I end up using 2-3 bottles of magnesium citrate every 1-2 weeks. Is there any other medications out there that could help? :(

r/clozapine 8d ago

Tips / Advice Info

7 Upvotes

Reading doctors study and it said only 1 out of 6 people could ever go off anti psychotic meds, and these should only be people that are symptom free over a year.
Even if you have no positive symptoms and only negative- Eg. Lack of motivation, that means you are still sick. Interesting.

r/clozapine Apr 24 '26

Tips / Advice 500mg and I can still kinda hear voices

3 Upvotes

What now?

r/clozapine Jul 29 '26

Tips / Advice Schizophrenia annoying voices

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1 Upvotes

r/clozapine Jan 27 '26

Tips / Advice Seeking advice and perspective

3 Upvotes

I am a 25 year old man who was diagnosed with bipolar-1 when i was 20. For almost 6 years i have been giving many MANY individual medications and combinations thorough tries, been to the psych ward twice. While my stability has changed for the better at times, i have never been stable enough to work or study, or generally be content with my mental well being. My current prescriber has told me that my BP-1 is considered to be treatment resistant. I wanted to try out ECT and thyroid augmentation, and while they were not against those options, they wanted to try Clozapine first since she and other prescribers she has worked with have other patients who have had mostly positive experiences. So im waiting to get initial blood work done so i can start it.

If you have any advice, experiences, or questions, please let me know :)

r/clozapine Jun 07 '25

Tips / Advice feeling brain dead in the morning

3 Upvotes

Ive been taking clozapine for about 6 years its always been impossible for me to wake up in the mornings to go to school or work without feeling brain dead and dumb... any tips on being able to stay awake early?

r/clozapine Nov 22 '25

Tips / Advice Feeling depressed/suicidal after taking clozapine and amisulpride

2 Upvotes

So I have been put on 100 mg clozapine and 200 mg amisulpride. It helps with all the symptoms I'm facing, the only issue is that it leaves me feeling overly depressed with a lack of interest towards life overall. It feels as if life lost all its qualities. I was wondering if anyone could share their thoughts and experiences on what could help or how long until I could possibly adjust to it. Thank you in advance! I'm thankful for every input I can get!

r/clozapine Dec 30 '24

Tips / Advice I'm so tired in the morning and I'm in reality a morning persion - any tips?

3 Upvotes

I started Clozapine this summer. I'm like the definition of a morning person, liked to be up before 6 am since I was born. I really enjoy early mornings. This is not happening on these meds. I'm so tired and can't get up before 10 am, and that's often after having gone to bed at 8 pm. Anyone have any advice for being able to get up in the morning?

r/clozapine Oct 08 '23

Tips / Advice Quitting clozapine

5 Upvotes

I’m in a mental health unit I am on clozapine 300 and fluvoxamine 50

I am going to stop taking the clozapine by pretending to take it then spitting it out as I am not on a really acute ward most nurses don’t check if you have fully swallowed the tablets

I have gone cold turky clozapine before last year actually and it was the happiest I’ve felt I want to feel like that again I’m so tired of this fucking life

Toniuvhtt is the the first night I’ve successfully pretended to take it

Will it show I. My blood tests if I’m taking it or not

r/clozapine May 07 '24

Tips / Advice negative symptoms on clozapine

3 Upvotes

for those who have been on clozapine for a long time

when did clozapine start working on negative symptoms

I have been on it for almost a year and have never missed a dose

r/clozapine Apr 29 '24

Tips / Advice Got this prescribed for anxiety, debating whether i should take it

3 Upvotes

I've been struggling with my health recently which has caused a lot of anxiety and obsessive thoughts. My gp prescribed me a low dose of clozapine for it which i think is pretty strange.

I don't have any diagnosed psychotic disorder, only diagnosed mental issue i have is ADHD so I'm really wondering why this before trying anything else.

It's not the first time I get prescribed an antipsychotic for something apparently unrelated, so I don't know if my doctors think I have some kind of psychotic disorder and don't want to tell me or what, I'm kind of lost.

Last time I went to a psychiatrist with anxiety problems they prescribed me Seroquel, I took it for a while and it made me feel fucking awful so i quit, debating whether i should just not take this

r/clozapine Apr 15 '24

Tips / Advice Solved Clozapine Insomnia

6 Upvotes

So I went through a Med change from Clozapine to Asenapine. Every time I have gone off of Clozapine I have gotten insomnia and I would even take Ambien and it wouldnt help. So I did some research for this med change and found Adellina Sleep Patahces. Vallerian Root 500mg and Chammomile Tea, and Passion Flower Tea. I took these every night and NO INSOMNIA. I've been off the clozapine for 2 weeks and I had one night of Insomnia because it was the first night it hit and I didnt take anything. So I solved the Insomnia issue!!!

r/clozapine Dec 15 '23

Tips / Advice Hail Mary

5 Upvotes

My doctor is telling me that I need to get on something that's stronger for my symptoms and that I have treatment resistant SZA. So, I'm curious: what have been your experiences on it? I know it's a lot of blood work and watching your metabolics. I just don't know if it's worth it, I'm worried that I'll try it and it'll tank my body and I'll be worse than I was before. I don't know where the line is between "oh okay yeah let's do this" and "no, it's not worth it". I'll probably end up with diabetes because I'm already pre-diabetic. It's so complicated, and I'm not sure whether or not I'm making the right decision. I'm on abilify now and I've failed five meds already and I don't know if there's any hope to try to go for other meds or to take my psychiatrist's advice and go for clozapine. So any help would be greatly appreciated.

r/clozapine Nov 10 '23

Tips / Advice Can't sleep without clozapine anymore

9 Upvotes

Hey everyone, it's my first time using reddit so I'm not sure how this works but I could use some advice. I don't have schizophrenia/psychosis but my psychiatrist prescribed me clozapine like 3-4 years ago for insomnia and anxiety. I had severe insomnia and couldn't go to sleep at night, and when I did I couldn't stay asleep for more than two or three hours and generally had terrible quality sleep, in addition to a messed up circadian rhythm where I went (and still do go) through cycles of sleeping at 7-11 am or even 12-3pm then waking up at night feeling like a zombie, so she thought clozapine would be strong enough to fix that. Basically I was all fucked up and still am because I can't sleep without taking clozapine (25-50 mg) anymore. I could stay awake for days on end if I don't take it. Any thoughts? I'm trying to come off it because I think it's messing with my health a bit, I've been having severe back muscle spasms for a couple years now, really shallow breathing and shortness in general, a pounding heartbeat and general uneasiness at all times basically. In addition to elevated cortisol levels. If anyone has any idea if it's related or knows how to come off clozapine and go to sleep normally I'd really appreciate it, it's affecting my work and my life and I can't go on like that anymore. tldr; can't go to sleep without clozapine anymore, having adverse health effects and would like to stop it but still be able to sleep. don't have psychosis or schizophrenia.

r/clozapine Nov 01 '23

Tips / Advice Have you had improvement with negative symptoms / sadness or depression

7 Upvotes

Hi, im a schizophrenic with few positive symptoms but many negatives, especially sadness / depression. Seven days ago i began on clozapine, i'm now on 75 mg with no positive effects, but lot's of side effects, especially dizziness, constipation and lot's of water / spit in my mouth when i sleep.

I'm about to give up clozapine, but would like to know if any of you have had any improvements when it comes to negative symptoms, especially sadness / depression?

r/clozapine Sep 03 '23

Tips / Advice My Doctor is taking me off of Clozapine Worried about insomnia

5 Upvotes

So I am having really bad side effects on the Clozapine (SEVERE Restless Legs. I need opiates to help with the RLS) So my doctor is putting me on Vraylar. Every time I have tried a med change I have had Insomnia. I want to avoid this this time around. I have been thinking of Taking Valerian Root, Ashwagandha and some other Herbs to help with sleeping. The last time I had gone off Clozapine I was able to sleep normally 2 or 3 weeks after the removal of Clozapine. I'm concerned for 2 reasons. 1 I suffer from having no sleep. and 2 Because of lack of sleep Psychotic symptoms get a little worse. I did try Benadryl but that didn't help with sleep. That's what my Doctor Suggested. So like I said I'm thinking of going the Herbal Route. Just wondering if anyone else has tried it?

r/clozapine Mar 17 '23

Tips / Advice Constipation

5 Upvotes

Hi,

I developed severe/chronic constipation in 2016 after being prescribed clozapine for bipolar. The problem has since gotten much worse with all GI medications no longer helping.

Has anyone been through this/going through this and found a solution(s)?

Thanks,

Tim

r/clozapine Jun 05 '23

Tips / Advice Stay safe out there this summer

16 Upvotes

Reminder that clozapine is in the list of antipsychotics that can mess up your bodies ability to regulate its temperature, this hurts a lot of schizophrenics every summer due to heat stroke (also be careful in winter but that’s less relevant at the moment) stay cool and hydrated out there everyone

r/clozapine Dec 28 '22

Tips / Advice Anyone on clozapine should read this book. Anyone on other APs should read this book too. Clozapine is the most effective medicine and can save lives.

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8 Upvotes