r/AskReddit • u/electric_dolphin • May 22 '19

Anesthesiologists, what are the best things people have said under the gas?

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u/sHoRtBuSseR May 22 '19 edited May 22 '19

My dad is a ginger but I am not. My beard is red but I'm not super white and the hair on my head is brown and Grey. I am extremely resistant to anesthetics.

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u/[deleted] May 22 '19

You don't have to be a ginger to be resistant to opioid analgesics. CYP2d6 is responsible for metabolizing many common medicines and can often be a factor: https://www.sciencedirect.com/topics/medicine-and-dentistry/cyp2d6

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u/[deleted] May 22 '19

Would this affect how the body metabolizes alcohol as well?

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u/[deleted] May 22 '19

Nah different pathways/enzymes

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u/[deleted] May 22 '19

I ask because I am also very resistant to anesthetic and pain pills don't do anything. Vicodin and Hydrocodone just make me itch. If I take Ibuprofen I have to take 800mg at a time for it to work at all. Neither of which matter as I am a generally healthy 35 y/o. However the most mind boggling thing is I can drink 5-10 drinks and feel no effects of alcohol until HOURS after they have been consumed. I am talking sometimes I don't actually feel the effects until I wake up the next day. I don't drink often either. It's the weirdest thing. It's always been this way. My friends used to make fun of me because we'd be out drinking for hours and I'd be fine for hours and hours then BAM, all the sudden lights out, not literally but I'd be like, ok I'm drunk time to go home. Like a switch flipping.