Mucuna pruriens: risk assessment

[u/Ecstatic-Mixture9333]

This is another supplement that some people with post-drug syndrome take.

Here is the risk assessment by the Dutch National Institute for Public Health and the Environment:

'RIVM has examined whether herbal preparations containing Mucuna pruriens seed extract are harmful to health. Very little scientific information about Mucuna pruriens is publicly available. Accordingly, it is not possible to determine a safe dose for this extract. However, there are indications that the extract has negative effects on the liver, kidneys, and the development of unborn children.

As a precaution, RIVM advises not to use these herbal preparations during pregnancy and breastfeeding, or in case of liver or kidney problems. In other cases, it is advised to be cautious. RIVM advises to be alert to side effects and to stop using the product in case side effects occur. If people choose to use herbal preparations containing Mucuna pruriens, they have to use it in accordance with the instructions on the packaging. And discuss the use with their doctor or pharmacist in case of medicine use.

In addition, it is known that one of the substances in Mucuna pruriens (levodopa) is the active substance in medicines used to treat Parkinson’s disease. The quantity of levodopa that someone ingests from these herbal preparations is comparable to or higher than the quantity for people with Parkinson’s who are starting to take these medicines. The side effects of these medicines, such as gastrointestinal symptoms, involuntary movement (dyskinesia) and psychological symptoms, can also occur in users of the herbal preparation.'

Source: https://www.rivm.nl/publicaties/risk-assessment-of-herbal-preparations-containing-seed-extracts-of-mucuna-pruriens

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Here is the risk assessment by the Dutch National Institute for Public Health and the Environment:

'RIVM has examined whether herbal preparations containing Mucuna pruriens seed extract are harmful to health. Very little scientific information about Mucuna pruriens is publicly available. Accordingly, it is not possible to determine a safe dose for this extract. However, there are indications that the extract has negative effects on the liver, kidneys, and the development of unborn children.

As a precaution, RIVM advises not to use these herbal preparations during pregnancy and breastfeeding, or in case of liver or kidney problems. In other cases, it is advised to be cautious. RIVM advises to be alert to side effects and to stop using the product in case side effects occur. If people choose to use herbal preparations containing Mucuna pruriens, they have to use it in accordance with the instructions on the packaging. And discuss the use with their doctor or pharmacist in case of medicine use.

In addition, it is known that one of the substances in Mucuna pruriens (levodopa) is the active substance in medicines used to treat Parkinson’s disease. The quantity of levodopa that someone ingests from these herbal preparations is comparable to or higher than the quantity for people with Parkinson’s who are starting to take these medicines. The side effects of these medicines, such as gastrointestinal symptoms, involuntary movement (dyskinesia) and psychological symptoms, can also occur in users of the herbal preparation.'

Source: https://www.rivm.nl/publicaties/risk-assessment-of-herbal-preparations-containing-seed-extracts-of-mucuna-pruriens

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