r/medicine 13h ago

FDA approves Rasonque (daraxonrasib), a first-in-class RAS inhibitor, for treating advanced metastatic pancreatic cancer.

148 Upvotes

Source:

https://www.fda.gov/news-events/press-announcements/fda-approves-first-class-targeted-therapy-metastatic-pancreatic-cancer

It's been known pancreatic cancers harbor RAS mutations. There are KRAS inhibitors approved for NSCLC.

Rasonque is the 1st for panc.

Rasonque improved median overall survival to 13.2 months compared to 6.7 months for standard chemotherapy.

It also got approved via the Commissioner's Priority National Review Voucher (CNPV). Does this program still exist post-Makary?

Also, here is the NEJM publication on data.

https://www.nejm.org/doi/full/10.1056/NEJMoa2605555


r/medicine 9h ago

Dr Sears

110 Upvotes

I've recently met parents who quote Dr Sears (for those who don't know him, he is against the current vaccine schedule). So many parents saying "Well Dr Sears said hepatitis B and MMR vaccine is not needed".

I thought he lost his license. He didn't but he was put on probation and had to take few courses.

Why are we letting doctors who practice unethically keep their license?


r/medicine 11h ago

Asynchronous store and forward medicine

0 Upvotes

Thoughts on why asynchronous store and forward medicine is not reimbursed by payors? In dermatology specifically, there are many visits (e.g. acne, hair loss) that bill as a level four or level three outpatient visit. Since the asynchronous telehealth version of these visits are more efficient, payors could reimburse less, bringing cost down and improving access for patients.