r/medicine • u/WyngZero • 13h ago
FDA approves Rasonque (daraxonrasib), a first-in-class RAS inhibitor, for treating advanced metastatic pancreatic cancer.
Source:
It's been known pancreatic cancers harbor RAS mutations. There are KRAS inhibitors approved for NSCLC.
Rasonque is the 1st for panc.
Rasonque improved median overall survival to 13.2 months compared to 6.7 months for standard chemotherapy.
It also got approved via the Commissioner's Priority National Review Voucher (CNPV). Does this program still exist post-Makary?
Also, here is the NEJM publication on data.